Coding

Part:BBa_K364001:Design

Designed by: Ophir Keret   Group: iGEM10_Debrecen-Hungary   (2010-06-30)

Human VDR DBD


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Compatibility with other parts Biobrick of the nuclear hormone receptor kit

Design Notes

The reconstruction of the DBD to the hinge region and LBD will be done with RFC 25.

Three dimensional structure

Source

Human VDR (of the nuclear hormone receptor superfamily)

References

1. "Cloning and expression of full-length cDNA encoding human vitamin D receptor.":[http://www.ncbi.nlm.nih.gov/pubmed/2835767] Baker A.R., McDonnell D.P., Hughes M., Crisp T.M., Mangelsdorf D.J., Haussler M.R., Pike J.W., Shine J., O'Malley B.W. Proc. Natl. Acad. Sci. U.S.A. 85:3294-3298(1988) [PubMed: 2835767] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].